Season 2 of Blue Eye Samurai continues Mizu's quest for vengeance in 17th-century Japan. The narrative expands internationally, with Mizu journeying to London in pursuit of her enemies. The season will feature six episodes, a reduction from the previous season's eight.

Returning characters include Taigen, Ringo, and Akemi, with hints that some presumed-dead characters may reappear. Production is underway, with a 2026 release expected.